|Normal Bone Structure|
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- Have a family history, especially in a parent, sibling, or child
- Are of Northern European decent
- Are aged 55 years or older
- Chronic bone pain, especially legs, hips, or spine
- Swelling or deformity of a limb
- Broken bones
- Bowing of a limb
- Damaged cartilage in the joints
- Increased head size
- Facial pain
- Hearing loss
- Pain medications, such as acetaminophen, or non-steroidal anti-inflammatory drugs (NSAIDs)
- Bone fracture
- Severe degenerative arthritis
- Bone deformity
- Calcium, usually about 1,000-1,500 mg per day
- Intake of adequate vitamin D, usually about 400 mg per day (older people may need more)
- Regular exercise to maintain skeletal health, joint mobility, and normal body weight
- Avoidance of excess mechanical stress on involved bones
- A splint for an area at high risk for fracture
NIH Osteoporosis and Related Bone Diseases National Resource Center http://www.niams.nih.gov
The Paget Foundation http://www.paget.org
The Arthritis Society http://www.arthritis.ca
Osteoporosis Canada http://www.osteoporosis.ca
Albagha OM, Genetic Determinants of Paget's Disease (GDPD) Consortium. Genome-wide association identifies three new susceptibility loci for Paget's disease of bone. Nat Genet . 2011;43(7):685-689.
Michou L, Brown JP. Emerging strategies and therapies for treatment of Paget's disease of bone. Drug Des Devel Ther . 2011;5:225-239.
Paget disease of bone. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed/what. Updated May 23, 2013. Accessed July 31, 2013.
Schneider D, Hofmann MT, et al. Diagnosis and treatment of Paget's disease of bone. Am Fam Physician . 2002;15;65(10).
What is Paget's disease of bone? NIH Osteoporosis and Related Bone Diseases National Resource Center website. Available at: http://www.niams.nih.gov/Health%5FInfo/Bone/Pagets/pagets%5Fdisease%5Fff.asp. Updated May 2009. Accessed July 31, 2013.
- Reviewer: John C. Keel, MD
- Review Date: 06/2013 -
- Update Date: 06/01/2013 -