The bile acid sequestrant drugs are among the earliest class of medications used to lower cholesterol. They are seldom prescribed today because of their many side effects.
Medications in the bile acid sequestrant family include cholestyramine resin (Locholest, Prevalite, Questran, Questran Light) and colestipol hydrochloride (Colestid) among others.
Bile acid sequestrants have been reported to impair the absorption of numerous nutrients, including
It appears, however, that only folate supplementation may be needed by individuals on long-term therapy with bile acid sequestrants. Although the bile acid sequestrant used in the studies interfered with the absorption of the other nutrients, their levels remained in the normal range. Just to be safe, though, making sure to get enough vitamin E and vitamin A (in the form of beta-carotene) would make sense.
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.