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Reducing Your Risk of End-Stage Renal Disease (ESRD)

To help reduce your risk of ESRD, follow these guidelines:

Maintaining a normal blood pressure may prevent kidney failure. Have your blood pressure checked regularly. If you have high blood pressure, take your blood pressure medications as ordered by your doctor and follow up regularly.

Maintaining blood glucose levels as close to normal as possible helps to prevent kidney disease. Have your glucose checked regularly if you are at risk for diabetes. If you have diabetes, follow the medication, diet, and exercise plan recommended by your doctor.

Lowering both cholesterol and triglyceride levels to the normal range can slow the progression of renal failure. The statin drugs are commonly used for this purpose.

Proteinuria is leakage of protein in the urine. Aggressive treatment of proteinuria with drugs, such as angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers, has been effective in slowing the deterioration of renal function in people with chronic renal failure.

Overuse of over-the-counter pain medication and illegal drugs can damage the kidneys. Take medications only as directed.

Revision Information

  • Chronic kidney disease (CKD) in adults. EBSCO DynaMed Plus website. Available at: http://www.dynamed.com/topics/dmp~AN~T115336/Chronic-kidney-disease-CKD-in-adults. Updated August 23, 2016. Accessed October 4, 2016.

  • What I need to know about kidney failure and how it's treated. National Institute of Diabetes and Digestive and Kidney Diseases website. Available at: http://www.niddk.nih.gov/health-information/health-topics/kidney-disease/kidney-failure-choosing-a-treatment-thats-right-for-you/Pages/ez.aspx. Updated September 2013. Accessed November 17, 2016.

  • Yu HT. Progression of chronic renal failure. Arch Int Med. 2003;163(12):1417-1429.